Trial Name | Status | Phase | Country | City |
---|---|---|---|---|
Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia The aim of this trial is to test the side effects of a drug called larotrectinib in people with previously untreated TRK gene fusion solid tumors. This trial is for several types of cancer. People wit... |
Active, not recruiting | Phase 2, | United States, Canada, | Birmingham, Little Rock, Downey, Los Angeles, Oakland, Orange, San Francisco, Aurora, Denver, New Haven, Wilmington, Washington, Fort Lauderdale, Fort Myers, Gainesville, Jacksonville, ... |
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors The aim of this trial is to test the safety and response to a drug called metarrestin in people with cancer that has spread. This trial is for several types of cancer. People with osteosarcoma may be ... |
Recruiting | Phase 1, | United States, | Fairway, Bethesda, |
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer The aim of this trial is to test licenced drugs in cancers that are not responding to treatment. The drugs tested will depend on the genetics of the cancer. Certain genetic changes are more sensitive ... |
Recruiting | Phase 2, | United States, | Birmingham, Phoenix, Auburn, Berkeley, Los Angeles, Oakland, Palo Alto, Roseville, Sacramento, San Francisco, San Jose, San Leandro, Santa Clara, Santa Cruz, Sunnyvale, Vallejo, Walnut... |
Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study The aim of this trial is to test different drugs on cancers with specific genetic mutations. The trial will assess how effective the drugs are at treating the cancer. Participants will be assigned to ... |
Recruiting | Phase 2, | United States, Australia, Belgium, Brazil, Canada, China, Denmark, France, Germany, Hong Kong, Israel, Italy, Japan, Korea, Republic of, Netherlands, New Zealand, Poland, Portugal, ... | Daphne, Goodyear, Duarte, Los Angeles, Newport Beach, Sacramento, San Francisco, Santa Monica, Newark, Gainesville, Miami, Ocala, Athens, Boise, Zion, Lafayette, Scarborough, Silver S... |
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors The aim of this trial is to test the safety and side effects of a drug called HFB200301 in people with advanced cancer. This trial is for several types of cancer. People with osteosarcoma may be able ... |
Recruiting | Phase 1, | United States, Spain, | Scottsdale, Los Angeles, Jacksonville, Rochester, Saint Louis, Houston, Fairfax, Barcelona, Madrid, Valencia, |
Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!") The aim of this trial is to implement and evaluate the use of educational booklets for children during their cancer journey. The aim is to improve the well-being and mental health of childhood cancer ... |
Recruiting | Not Applicable, | Austria, Germany, Italy, Switzerland, | Linz, St. Veit, Graz, Salzburg, Vienna, Nürnberg, Frankfurt am Main, Hannover, Essen, Münster, Homburg, Leipzig, Bad Oeynhausen, Berlin, Bielefeld, Cologne, Dresden, Erlangen, Hamb... |
Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors The aim of this trial is to test the side effects and best dose of natural killer cells in combination with the chemotherapy drugs cyclophosphamide and etoposide. They are testing this in several type... |
Recruiting | Phase 1, | United States, | Houston, |
Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors This phase I trial is studying the side effects and best dose of erlotinib when given with temozolomide in treating young patients with recurrent or refractory solid tumors. Erlotinib may stop the gro... |
Completed | Phase 1, | United States, | Arcadia, |
cfMeDIP-seq Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease This trial aims to collect genetic data from cancers to see if it can be used to detect cancer and identify any cancer left after treatment. It will be compared with data from non-cancer patients. Th... |
Recruiting | United States, | Duarte, Rochester, Cleveland, Portland, Memphis, Nashville, Austin, | |
SPEARHEAD-3 Pediatric Study The aim of this trial is to test the safety and effectiveness of the drug afamitresgene autoleucel in children and young people with MAGE-A4 positive cancer. This includes people with osteosarcoma. E... |
Not yet recruiting | Phase 1, Phase 2, | United States, | Palo Alto, Aurora, New York, Seattle, |
Trial Name:
Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute LeukemiaThe aim of this trial is to test the side effects of a drug called larotrectinib in people with previously untreated TRK gene fusion solid tumors. This trial is for several types of cancer. People wit...
Status:
Active, not recruiting
Phase:
Phase 2,
Country:
United States, Canada,
City:
Birmingham, Little Rock, Downey, Los Angeles, Oakland, Orange, San Francisco, Aurora, Denver, New Haven, Wilmington, Washington, Fort Lauderdale, Fort Myers, Gainesville, Jacksonville, ...
Trial Name:
Metarrestin (ML-246) in Subjects With Metastatic Solid TumorsThe aim of this trial is to test the safety and response to a drug called metarrestin in people with cancer that has spread. This trial is for several types of cancer. People with osteosarcoma may be ...
Status:
Recruiting
Phase:
Phase 1,
Country:
United States,
City:
Fairway, Bethesda,
Trial Name:
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage CancerThe aim of this trial is to test licenced drugs in cancers that are not responding to treatment. The drugs tested will depend on the genetics of the cancer. Certain genetic changes are more sensitive ...
Status:
Recruiting
Phase:
Phase 2,
Country:
United States,
City:
Birmingham, Phoenix, Auburn, Berkeley, Los Angeles, Oakland, Palo Alto, Roseville, Sacramento, San Francisco, San Jose, San Leandro, Santa Clara, Santa Cruz, Sunnyvale, Vallejo, Walnut...
Trial Name:
Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform StudyThe aim of this trial is to test different drugs on cancers with specific genetic mutations. The trial will assess how effective the drugs are at treating the cancer. Participants will be assigned to ...
Status:
Recruiting
Phase:
Phase 2,
Country:
United States, Australia, Belgium, Brazil, Canada, China, Denmark, France, Germany, Hong Kong, Israel, Italy, Japan, Korea, Republic of, Netherlands, New Zealand, Poland, Portugal, ...
City:
Daphne, Goodyear, Duarte, Los Angeles, Newport Beach, Sacramento, San Francisco, Santa Monica, Newark, Gainesville, Miami, Ocala, Athens, Boise, Zion, Lafayette, Scarborough, Silver S...
Trial Name:
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid TumorsThe aim of this trial is to test the safety and side effects of a drug called HFB200301 in people with advanced cancer. This trial is for several types of cancer. People with osteosarcoma may be able ...
Status:
Recruiting
Phase:
Phase 1,
Country:
United States, Spain,
City:
Scottsdale, Los Angeles, Jacksonville, Rochester, Saint Louis, Houston, Fairfax, Barcelona, Madrid, Valencia,
Trial Name:
Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")The aim of this trial is to implement and evaluate the use of educational booklets for children during their cancer journey. The aim is to improve the well-being and mental health of childhood cancer ...
Status:
Recruiting
Phase:
Not Applicable,
Country:
Austria, Germany, Italy, Switzerland,
City:
Linz, St. Veit, Graz, Salzburg, Vienna, Nürnberg, Frankfurt am Main, Hannover, Essen, Münster, Homburg, Leipzig, Bad Oeynhausen, Berlin, Bielefeld, Cologne, Dresden, Erlangen, Hamb...
Trial Name:
Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid TumorsThe aim of this trial is to test the side effects and best dose of natural killer cells in combination with the chemotherapy drugs cyclophosphamide and etoposide. They are testing this in several type...
Status:
Recruiting
Phase:
Phase 1,
Country:
United States,
City:
Houston,
Trial Name:
Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid TumorsThis phase I trial is studying the side effects and best dose of erlotinib when given with temozolomide in treating young patients with recurrent or refractory solid tumors. Erlotinib may stop the gro...
Status:
Completed
Phase:
Phase 1,
Country:
United States,
City:
Arcadia,
Trial Name:
cfMeDIP-seq Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseThis trial aims to collect genetic data from cancers to see if it can be used to detect cancer and identify any cancer left after treatment. It will be compared with data from non-cancer patients. Th...
Status:
Recruiting
Phase:
Country:
United States,
City:
Duarte, Rochester, Cleveland, Portland, Memphis, Nashville, Austin,
Trial Name:
SPEARHEAD-3 Pediatric StudyThe aim of this trial is to test the safety and effectiveness of the drug afamitresgene autoleucel in children and young people with MAGE-A4 positive cancer. This includes people with osteosarcoma. E...
Status:
Not yet recruiting
Phase:
Phase 1, Phase 2,
Country:
United States,
City:
Palo Alto, Aurora, New York, Seattle,