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Trial Phase ID/ NCT Number
Trial Name Status Phase Country City
Investigating Cognitive Impairment in Young Patients With Cancer Prospectively

This trial will investigate the brain function of children, adolescents and young adults during and after chemotherapy treatment. It will test cognitive skills such as memory and attention, the brain'...

Recruiting Denmark, Copenhagen,
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue Tumors

This trial will assess the safety and effectiveness of a drug called an oncolytic virus in sarcoma. This includes people with osteosarcoma that has returned or not responded to standard treatment.

Recruiting Early Phase 1, China, Xi'an,
ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas

HS-20093 is a fully humanized IgG1 antibody-drug conjugate (ADC) which specifically binds to B7-H3, a target wildly expressed on solid tumor cells. This is a phase 2, open-label, multi-center study t...

Not yet recruiting Phase 2,
Extracorporeal Shock Wave Therapy on Osteoblast-Like Cells In- Vitro Study

The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy (ESWT) has recently become popular. It has been widely used in medical practice...

Completed Not Applicable, India, Bengaluru,
3D Printed Personalized Extendable Prosthesis

The goal of this type of observational study is to investigate the preliminary effect of 3D printed personalized extendable prosthesis replacement on limb salvage in children with osteosarcoma. The ma...

Completed China, Chongqing,
Quality of Life of Patients With Bone Tumor of the Lower Limbs Treated With Salvage Surgery

The aim of the study is to describe, through a minimum follow-up of 18 months, the quality of life of patients undergoing salvage surgery of lower limb for musculoskeletal tumors and to identify possi...

Enrolling by invitation Italy, Bologna,
Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery

This trial will look to see if bone cancer patients will adhere to a home-based exercise programme. Exercise programmes can help bone cancer patients to gain independence after surgery. They can also ...

Recruiting Italy, Bologna,
Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma

Former bone cancer patients can develop chronic (long-term) pain. Cognitive behavioural therapy (CBT) is a non-invasive option for treating this pain. However, CBT programmes have not been adapted to ...

Recruiting Not Applicable, United States, Memphis,
Immunotherapy for Recurrent Osteogenic Sarcoma

This will be a phase II, single arm study of osteosarcoma patients with fully resected pulmonary metastases. The MTD corresponds to the dosage recommendations of the manufacturer of Iscador® P which ...

Not yet recruiting Phase 2, United States, Hackensack, Houston,
Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

This trial aims to find the dose and effectiveness of engineered natural killer (NK) cells that can be given with chemotherapy to treat cancers including osteosarcoma. The NK cells will be engineered ...

Recruiting Phase 1, Phase 2, United States, Houston,


  • ONTEX is intended to supplement, not replace, your healthcare team. Patients should always discuss a clinical trial with their healthcare team. If a patient is eligible for a trial the trial team will be able to provide more in-depth information about the trial so the patient can make an informed decision before taking part. Trial information has been sourced from The content is then reviewed weekly by the Osteosarcoma Now team. All the trials also have a patient-friendly summary and key information section written by the team at Osteosarcoma Now. We have also included a description of the medications being used in the trial and summarised the inclusion and exclusion criteria in the ‘who is this trial (not) for’ sections. To the best of our knowledge the clinical trial database is up-to-date and accurate.However, we cannot assume any liability for the accuracy or completeness of the information.