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Trial Phase ID/ NCT Number
Trial Name Status Phase Country City
Donor Site Morbidity After Free Vascularized Fibular Graft

This study was carried out at Assiut University to Asses the long-term donor site morbidity following free vascularized fibular transfer because there is a limited information regarding the long-term ...

Recruiting Egypt, Assiut,
Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

The participants of this study will be children, adolescents, and young adults with residual osteosarcoma, which cannot be removed completely through surgery. Participants will have achieved a partia...

Not yet recruiting Phase 2,
Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells

The aim of the trial This trial aims to look at the effectiveness of a drug called Narlumosbartmab (NB). Each group of patients will receive either neoadjuvant chemotherapy (NC) on its own, or with ...

Recruiting Not Applicable, China, Beijing,
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

The aim of the trial This trial aims to evaluate the safety and tolerability of KB707 in adults with advanced solid cancer, that is affecting the lungs. People with osteosarcoma can take part in thi...

Recruiting Phase 1, United States, El Paso, The Woodlands,
Hepato-pancreato-biliary Abnormalities in Fibrous Dysplasia of Bone/McCune Albright Syndrome

Fibrous dysplasia of bone /McCune Albright syndrome (FD/MAS) is a rare bone disease caused by somatic mutations in GNAS gene. This GNAS mutation predisposes to cancers, including breast cancer, thyroi...

Recruiting France, Angers, Bordeaux, Brest, Caen, Clermont-Ferrand, Lille, Lyon, Marseille, Montpellier, Nice, Paris, Poitiers, Rennes, Saint-Étienne, Strasbourg, Toulouse,
Adjuvant Therapy for High-risk Hepatocellular Carcinoma Post Liver Transplantation

Explore the impact of postoperative administration of multi-kinase inhibitors (including sorafenib, lenvatinib, and regorafenib) in conjunction with bevacizumab on post-transplant recurrence, overall ...

Not yet recruiting Phase 2, China, Beijing,
Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy

Thanks to the intrinsic qualities of the proton beam, proton therapy will reduce adverse effects of irradiation. The Proteus®One is the latest generation of proton therapy equipment, enabling the Cen...

Recruiting Not Applicable, France, Nice,
Evaluation of Performance Characteristics and Applicability in Oncology of Devices Customized Medical Devices Made by 3D Printing

The aim of the trial This trial aims to look at the usefulness of using 3D printing to create reconstructive bones and tissue in different cancer patients. This includes children with osteosarcoma.

Recruiting Not Applicable, Italy, Firenze, Siena,
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors

9 participants are expected to be enrolled for this open,Single-armed clinical trial to evaluate the safety and efficacy of the recombinant herpes simplex virus Ⅰ, R130 in patients with advanced b...

Recruiting Early Phase 1, China, ShangHai,
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

Pediatric subjects aged 6-17 with biopsy confirmed cancer and imaging findings suspicious for pulmonary metastatic disease scheduled to undergo pulmonary metastasectomy via and open or minimally invas...

Not yet recruiting Phase 1,


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