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Dalam 30 tahun terakhir hanya ada sedikit perubahan pada pengobatan osteosarkoma (OS). Kami berdedikasi untuk mengubah ini. Melalui Kepercayaan Myrovlytis, kami mendanai penelitian OS, dengan fokus menemukan perawatan baru. Kami dengan senang hati mengumumkan bahwa kami telah memberikan dana kepada Dr Wolfgang Paster di Children's Kanker Lembaga Penelitian, Wina, Austria.

Cancer immunotherapy, where the patient’s own immune system is boosted to fight the cancer, has transformed the outlook for many cancers. However, for OS this has proven to be challenging. OS tumours are very good at hiding from the body’s own immune system. One of the key players in the immune system are T cells. These cells can recognise and kill target cells, including cancer cells. If we can identify targets of these T cells that are only found in OS cells, we may be able to develop new treatments and overcome some of the previous barriers to immunotherapy.

In this 1 year project, Wolfgang’s team will use cutting edge techniques to identify proteins that are only found in OS tumour samples. They will then test whether these proteins can be recognised by T cells in the laboratory. In the future, they hope that they will be able to use these target proteins as the basis for new therapies such as vaksin tumor.

Tonton video singkat di bawah ini dari Wolfgang yang menjelaskan karyanya atau membaca ringkasan proyek. Sebuah transkrip video juga tersedia.

Kami akan terus mendanai penelitian ke dalam OS dan memajukan penelitian. Kami baru saja meluncurkan putaran pendanaan kami untuk tahun 2023. Temukan lebih banyak tentang apa yang kita dana dan bagaimana menerapkan. Kami juga menerima pertanyaan informal melalui e-mail.