Inform, Empower, Connect

Summarising clinical trials

                   Navigating osteosarcoma

Sharing the latest research 

Signposting to support

                                Highlighting events

Summarising clinical trials

           Navigating osteosarcoma

Sharing the latest research 

Signposting to support 

                         Highlighting events 

Scientists doing experiments in the labratory

We strongly believe that wherever you live in the world information about clinical trials should be available to you. Our curated clinical trial database (ONTEX) summarises trials from across the globe to make your search easier.

We also have resources to help you better understand clinical trials.


Blog


Clinical Trials


Patient Toolkit

Glossary

Being diagnosed with osteosarcoma can feel like having to learn a whole new language.  Here you can find definitions for words your doctor is likely to use.

Support Groups

There are so many wonderful organisations dedicated to supporting the osteosarcoma community. Search our interactive map for information about organisations near you.

New Phase III Osteosarcoma Trial Reports Positive Results

There has been encouraging news from a Phase III clinical trial investigating a new treatment for people with relapsed or refractory osteosarcoma. What is the treatment? The treatment, called Ris-Rez (risvutatug rezetecan), is a type of targeted therapy known as an...

OST-HER2 Update: New FDA Milestone

Osteosarcoma Now has been following the development of OST-HER2, one of the most advanced investigational therapies currently being developed specifically for osteosarcoma. Over the past three years, we have reported on the progression of the Phase 2b clinical trial,...

How Dogs Could Help Unlock New Treatments for Osteosarcoma

Tufts University Joins Global Effort to Find Better Treatments for Osteosarcoma Veterinary oncologists at Tufts University are part of the largest coordinated osteosarcoma research initiative ever launched, using clinical trials in pet dogs to generate insights that...

New Research on Osteosarcoma Lung Metastasis

Research focuses on how osteosarcoma reaches the lungs and what may prevent it A research team at Oregon Health and Science University (OHSU) has been awarded $3.17 million from the National Institutes of Health to develop new laboratory models designed to better...

Cabozantinib in Osteosarcoma: What We Know So Far

Treatment for osteosarcoma has remained largely unchanged for decades, particularly for patients with metastatic or relapsed disease. Targeted therapies are now being explored as a way to improve outcomes. One of these is cabozantinib, a drug currently being studied...

New Hope in Preventing Osteosarcoma Lung Metastasis

New Research Exploring FAK Inhibitors to Prevent Osteosarcoma Lung Metastasis   Researchers are exploring a new strategy to stop osteosarcoma from spreading to the lungs, one of the biggest challenges in treating this aggressive bone cancer. A team at Colorado...

Looking Ahead to 2026 Reflections on a Year of Change at Osteosarcoma Now

In March 2025, we sadly lost the founder of the Osteosarcoma Now. His close personal connection to osteosarcoma led them to support the development of Osteosarcoma Now by funding the creation of the website and database. The work itself was carried out by a dedicated...

A New Step Forward: Targeting SFRP2 to Overcome Osteosarcoma Treatment Resistance co-funded by the Bardo Foundation

We are delighted to share an important milestone in osteosarcoma research and in the journey of The Bardo Foundation. A new scientific paper, co-funded by the Bardo Foundation with the Myrovlytis Trust, has been published. It marks the first-ever published paper from...

New Study Links Nerve Growth and Blood Vessels to Osteosarcoma Progression

Scientists at Johns Hopkins Medicine have uncovered an unexpected link between the nervous system and bone cancer growth. Their new study suggests that the nerves which carry pain signals might also be helping osteosarcoma tumours grow and spread. Osteosarcoma is the...

Mifamurtide after Surgery in Osteosarcoma: Who Might Benefit?

Mifamurtide after Surgery in Osteosarcoma: Who Might Benefit?A new analysis from Italy and Spain looked at almost 400 people (ages 4–40) with non-metastatic high-grade osteosarcoma of the arms or legs. It suggests that adding mifamurtide after surgery may help...

Partnerships

Osteosarcoma Institute
Sarcoma Uk: The bone and soft tissue charity

Bone Sarcoma Peer Support

Sarcoma Patient Advocate Global Network
Trust Paola Gonzato